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Juvenile dermatomyositis heilbar

Juvenile dermatomyositis (JDM) is a kind of arthritis that happens in kids. It's a rare disease that causes inflammation and swelling of the muscles and blood vessels under the skin.It may also be. Juvenile dermatomyositis has some similarities to adult dermatomyositis and polymyositis.It typically affects children ages 2 to 15 years, with symptoms that include weakness of the muscles close to the trunk of the body, inflammation, edema, muscle pain, fatigue, skin rashes, abdominal pain, fever, and contractures.Children with juvenile dermatomyositis may have difficulty swallowing and. What is juvenile dermatomyositis (JDM)? JDM is an autoimmune disease that affects muscle, skin and small blood vessels in children. The body's immune system attacks its own healthy muscle, skin and blood vessel tissues because it mistakenly sees them as invaders INTRODUCTION. Juvenile dermatomyositis (JDM) and juvenile polymyositis (JPM) are rare autoimmune myopathies affecting children. JDM is characterized primarily as a capillary vasculopathy, whereas JPM involves direct T cell invasion of muscle fibers similar to that seen in adult polymyositis []. (See Clinical manifestations of dermatomyositis and polymyositis in adults.

Juvenile dermatomyositis (JDM) is a rare disease that affects muscles and skin. A disease is defined as juvenile when it starts before the age of 16. Juvenile dermatomyositis belongs to a group of conditions that are thought to be autoimmune diseases. Usually the immune system helps us to fight infections INTRODUCTION. Juvenile dermatomyositis (JDM) and juvenile polymyositis (JPM) are autoimmune myopathies of childhood. JDM is primarily a capillary vasculopathy, whereas JPM involves direct T cell invasion of muscle fibers similar to that seen in adult polymyositis [].However, as the diagnostic tools become more sophisticated (eg, biopsies that demonstrate inclusion body myositis or inflammatory.

Dermatomyositis, Amyopathic dermatomyositis, Idiopathic inflammatory myopathies, Petges-Clejat syndrome, Adult onset dermatomyositis, Juvenile onset dermatomyositis, Paraneoplastic dermatomyositis, Dermatopolymyositis. Authoritative facts from DermNet New Zealand Juvenile Myositis (JM) is found in children under the age of 18 and affects two to four children per million. The most frequent form of juvenile myositis is juvenile dermatomyositis (JDM), in which children experience marked muscle weakness and skin rash 4. Martin N, Krol P, Smith S, et al. Comparison of children with onset of juvenile dermatomyositis symptoms before or after their fifth birthday in a UK and Ireland juvenile dermatomyositis cohort study. Arthritis Care Res (Hoboken). 2012;64(11):1665-1672. 5. Magro CM, Segal JP, Crowson AN, Chadwick P Juvenile dermatomyositis (JDM) is a systemic inflammatory disease involving children, which primarily affects the skin and the musculoskeletal system. The characteristic findings include Gottron papules, heliotrope rash, calcinosis cutis, and symmetric proximal muscle weakness. Histologically, it is characterized by the presence of lymphocytic vascular inflammation and endothelial swelling

Juvenile dermatomyositis (JDM) can seriously impact your child's daily life, and can also tax the emotional health of your family. Since it's so rare, juvenile dermatomyositis (JDM) can seem scary to family and child—and often it's puzzling to pediatricians, who may not be familiar with the condition JDM = Juvenile Dermatomyositis Ser du etter generell definisjon av JDM? JDM betyr Juvenile Dermatomyositis. Vi er stolte over å liste akronym av JDM i den største databasen av forkortelser og akronymer. Det følgende bildet viser en av definisjonene av JDM på engelsk: Juvenile Dermatomyositis

Juvenile dermatomyositis (JDM) is rare muscle disease affecting approximately three children in every million per year. Muscle weakness and skin rashes are the main symptoms of JDM and it affects every child differently - some experience a mild form of the disease while others display a more severe disease progression Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications. It manifests itself in children; it is the pediatric counterpart of dermatomyositis.In JDM, the body's immune system attacks blood vessels throughout the body, causing inflammation called vasculitis Diagnostic criteria for Juvenile Dermatomyositis. Accessed 2/8/2019. National Institutes of Health, Office of Rare Diseases Research. Genetic and Rare Diseases Information Center (GARD) - Juvenile dermatomyositis. Accessed 2/8/2019. American College of Rheumatology. Dermatomyositis (Juvenile). Accessed 2/8/2019 Juvenile dermatomyositis: Latest advances. Wu Q(1), Wedderburn LR(2), McCann LJ(3). Author information: (1)Infection, Inflammation and Rheumatology Section, University College London Great Ormond Street Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, United Kingdom

Juvenile Dermatomyositis: Symptoms and Treatment

  1. Juvenile dermatomyositis (DM) is a chronic inflammatory disease affecting the muscles and skin . While juvenile DM is relatively rare, with an incidence of 2.5-4.1 cases per million children in the US , it is the most common inflammatory myopathy of childhood
  2. al pain in a girl with juvenile dermatomyositis
  3. Juvenile dermatomyositis (JDM) is a pediatric childhood-onset version of a severe autoimmune condition affecting skin and muscle. Although certain clinical features are common to both JDM and adult-onset dermatomyositis, the frequency of these features differs significantly, suggesting that the age of patients at the onset of disease affects disease processes
  4. Juvenile dermatomyositis (JDM) is an important subtype of dermatomyositis characterized by inflammation of muscle, skin and gastrointestinal tract. A 14-year-old girl,.

Dermatomyositis (DM) is a long-term inflammatory disorder which affects skin and the muscles. Its symptoms are generally a skin rash and worsening muscle weakness over time. These may occur suddenly or develop over months. Other symptoms may include weight loss, fever, lung inflammation, or light sensitivity. Complications may include calcium deposits in muscles or skin Juvenile Dermatomyositis (JDM) is an autoimmune condition which means that the immune system which normally protects the body reacts abnormally and becomes overactive in normal tissues. This immune system reaction leads to inflammation (pain/redness/swelling) which can lead to possible tissue damage. In dermatomyositis, the inflammation affects mainly the small blood vessels in muscle.

Juvenile dermatomyositis Genetic and Rare Diseases

Juvenile dermatomyositis (JDM) is a rare, often chronic autoimmune disease with onset during childhood. It is characterized by weakness in proximal muscles and pathognomonic skin rashes. Although the etiology remains unclear, it has been proposed that JDM is caused by a vasculopathy within the muscl Juvenile dermatomyositis is a rare childhood disease that causes muscle weakness and skin rash. Juvenile dermatomyositis (JDM) is a rare disease that causes inflammation of the blood vessels, muscles and skin. It affects about 3,000-5,000 kids in the United States. Most cases occur between the ages. Juvenile Dermatomyositis is a rare autoimmune disease characterized by muscle weakness and a skin rash. A healthy immune system protects your child from infection by attacking invaders such as viruses or other pathogens. In children with dermatomyositis,. Pierre Quartier, Romain K. Gherardi, in Handbook of Clinical Neurology, 2013. Abstract. Juvenile dermatomyositis (JDM) is a systemic, inflammatory, idiopathic disease, mainly affecting the skin and the muscles, starting before the age of 16, with an incidence around one case per 1 million children. Some patients display typical features of JDM without skin involvement, or even without muscle. If your child is being treated for juvenile dermatomyositis (JDM) at Boston Children's Hospital, your entire family is involved. As an interdisciplinary team, we partner closely with families to understand and address any individual, family or school issues which may arise as we work together to optimize your child's adjustment to the challenges of living with JDM

Juvenile Dermatomyositis: Symptoms, Causes, Treatment

Juvenile dermatomyositis (JDM) is a rare disease that causes muscle inflammation and a skin rash. Symptoms often first appear in children between ages 5 and 10. Symptoms include fever, rash, muscle weakness and pain, and calcium deposits under the skin Juvenile dermatomyositis (JDM) is a rare condition that causes inflammation of the skin and muscle. Inflammation is one of the body's protective responses to infection or injury, but in diseases such as JDM, uncontrolled inflammation can cause damage. Other parts of the body may also be affected such as the lung and intestines Juvenile dermatomyositis as a paraneoplastic phenomenon: an update. Morris P(1), Dare J. Author information: (1)University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, AR 72202, USA. morrispaulak@uams.ed Registries and biobanks for juvenile dermatomyositis (JDM) have generated statistical power to help understand pathogenesis and determine treatment and long-term outcomes in this rare and heterogeneous disease. Genotype, autoantibodies, muscle histology and early clinical features may predict progno Juvenile dermatomyositis (JDM) is a rare but complex and potentially life-threatening autoimmune disease of childhood, primarily affecting proximal muscles and skin

Juvenile Dermatomyositis is a rare, potentially life-threatening condition with no known cure. There is no published literature capturing how children and young people feel about their condition, from their perspective. This study was therefore unique in that it asked children and young people what is it like to live with Juvenile Dermatomyositis Juvenile dermatomyositis (JDM) is a rare disease that causes muscle inflammation and a skin rash. Symptoms often first appear in children between ages 5 and 10, but can occur at other ages. Children with JDM have weakness especially in the muscles around their neck, shoulders, and hips

Juvenile dermatomyositis and polymyositis: Diagnosis

Juvenile dermatomyositis (JDM) is a systemic, autoimmune inflammatory muscle disorder and vasculopathy that affects children younger than 18 years. JDM primarily affects the skin and the skeletal muscles. Characteristic findings include Gottron's papules, a heliotrope rash, calcinosis cutis, and symmetrical, proximal muscle weakness Juvenile dermatomyositis can make it hard for a child to take part in school and other activities. Work with your child's school to help teachers and caregivers understand your child's limits. A healthy lifestyle can help improve your child's quality of life Juvenile dermatomyositis (JDM) is a rare but complex and potentially life-threatening autoimmune disease of childhood, primarily affecting proximal muscles and skin. Although the cause of JDM remains unknown it is clear that genetic and environmental influences play a role in the aetiology Juvenile dermatomyositis (JDM) is a rare disease that causes muscle inflammation and a skin rash. Symptoms often first appear in children between ages 5 and 10. Symptoms include fever, rash, muscle weakness and pain, and calcium deposits under the skin. The condition also causes a rash.

Juvenile (childhood onset) dermatomyositis is a condition, which affects a number of systems of the body, although its main effects are seen in the muscles and skin. The underlying process is an inflammation of small blood vessels (vasculitis) which is thought to result from the presence in the blood of circulating immune complexes - combinations of antigen and antibody which are potent. Juvenile dermatomyositis is an inflammatory disease of the skin and muscles. While all ages and ethnic groups can be affected by dermatomyositis, the disorder is most common among children 5 to 14 years old

Juvenile Dermatomyositis (idiopathische juvenile Dermatomyositis, juveniler dermatopolymyositis) - schwere progressive systemische Erkrankung vor allem der quergestreiften Muskulatur zu beeinflussen, Haut und Blutgefäß des microvasculature. ICD-10-Code. M33.0. Jugendliche Dermatopolymyositis The aim was to assess environmental factors associated with disease flare in juvenile and adult dermatomyositis (DM). Methods. An online survey of DM patients from the USA and Canada examined smoking, sun exposure, infections, medications, vaccines, stressful life events and physical activity during the 6 months before flares, or in the past 6 months in patients without flares Abatacept is used in the treatment of adult rheumatoid arthritis and juvenile idiopathic arthritis, but there are very limited data regarding its use for calcinosis due to juvenile dermatomyositis . The mechanism of action of abatacept in JDM-associated calcinosis may be due to the inhibition of macrophages and consequent decrease in proinflammatory cytokines [ 14 ] Juvenile dermatomyositis is a autoimmune inflammatory conditions involving muscles. The juvenile form has a tendancy to be more severe and is less associated with an underlying malignancy than the adult form. Auto-antibodies are relatively specific for the condition -- the specific elevated muscle specific antibodies being anti-RNa and anti-Mi2 Juvenile dermatomyositis can make it hard for your child to take part in school and other activities. Work with your child's school to help teachers and caregivers understand your child's limits. A healthy lifestyle can help improve your child's quality of life. This includes a good diet, exercise and rest

Video: Juvenile Dermatomyositis - PRINT

Juvenile dermatomyositis and polymyositis: Treatment

Dermatomyositis DermNet N

Juvenile dermatomyositis. Juvenile dermatomyositis is an inflammatory disease that causes muscle weakness and a skin rash on the eyelids and knuckles. Approximately three in 1,000,000 children are affected by juvenile dermatomyositis. Juvenile dermatomyositis affects an estimated 3,000-5,000 children in the United States Sallum AM et al. (2002) Juvenile dermatomyositis: clinical, laboratorial, histological, therapeutical and evolutive parameters of 35 patients. Arq Neuropsiquiatr 60: 889-899 Sallum AM, Marie SK et al. (2004) Immunohistochemical analysis of adhesion molecule expression on muscle biopsy specimens from patients with juvenile dermatomyositis Juvenile dermatomyositis is an autoimmune systemic vasculopathy, mainly characterized by chronic inflammation of the striated muscle and skin. The authors report the case of a 15-year-old boy presenting with a four-month history of myalgia and proximal muscle weakness on the upper and lower limbs. These symptoms were associated with heliotrope palpebral exanthema, erythema in the dorsum of the. 1 Definition. Die Dermatomyositis, kurz DM, ist eine generalisierte, mesenchymale Erkrankung, die die Skelettmuskulatur, die Haut und die inneren Organe (Niere, Lunge, Herz) befällt.Fehlt bei systemischer Erkrankung die Hautbeteiligung, spricht man von einer Polymyositis.Ungefähr 15 bis 20 % der Dermatomyositiden - nach Ansicht mancher Autoren auch mehr - sind als paraneoplastisches Syndrom. Measures of adult and juvenile dermatomyositis, polymyositis, and inclusion body myositis: Physician and Patient/Parent Global Activity, Manual Muscle Testing (MMT), Health Assessment Questionnaire (HAQ)/Childhood Health Assessment Questionnaire (C-HAQ), Childhood Myositis Assessment Scale (CMAS), Myositis Disease Activity Assessment Tool (MDAAT), Disease Activity Score (DAS), Short Form 36.

Juvenile dermatomyositis: Introduction. Juvenile dermatomyositis: A very rare autoimmune disorder where the body's own immune system attacks blood vessels and causes them to become inflamed. The condition is characterized by progressive muscle weakness and a characteristic pinkish-purple rash Juvenile dermatomyositis is a rare, idiopathic inflammatory disease involving the striated muscles and the skin. Similar to adult cases of dermatomyositis, the disease is primarily characterized by progressive, symmetrical, proximal muscle weakness Juvenile dermatomyositis (juvenile idiopathic dermatomyositis, juvenile dermatopoly myositis) is a serious progressive systemic disease with a predominant lesion of the striated muscles, skin and vessels of the microcirculatory bed. ICD-10 code. M33.0. Youthful dermatopoly myositis Juvenile dermatomyositis (JDM) is a disease in children that causes skin rash (dermato) and muscle inflammation (myositis). It results in weak muscles. JDM is a type of autoimmune disease. The immune system is a group of cells that protect the body from infections. In autoimmune diseases such as JDM, these cells fight the body's own tissues and.

The diagnosis of juvenile dermatomyositis can be challenging when proximal muscle weakness develops without characteristic skin manifestations. In this patient, rash appeared 2 months after the onset of muscle weakness. As a result, the initial diagnosis was viral myositis, which led to delayed therapy Juvenile dermatomyositis causes muscle damage due to inflammation. Symptoms include fever, rash, muscle weakness and pain, and calcium deposits under the skin. The condition also causes a rash around the eyelids, knuckles, or finger joints. A rash may also occur on the elbows, knees, and ankles

Juvenile dermatomyositis (JDM) is an inflammatory disorder that affects the muscle, skin or blood vessels of children. It is also known as inflammatory myopathy. This disease can cause muscle weakness and skin rashes in kids, because it leads to inflammation and swelling of the muscles and blood vessels under the skin Juvenile dermatomyositis (JDM) is a rare, potentially life-threat-ening systemic autoimmune disease primarily affecting muscle and skin. Recent advances in the recognition, standardised assessment and treatment of JDM have been greatly facilitated by large collaborative research networks Juvenile Dermatomyositis (JDM) Clinic Information. Call the clinic if you or your child have had a cold, cough, diarrhea, fever or rash within two days of your appointment, or have been sick with or exposed to chicken pox in the last three weeks

Juvenile Myositis The Myositis Associatio

Juvenile dermatomyositis is the condition most often seen in children. What causes juvenile dermatomyositis? The cause of juvenile dermatomyositis has not yet been determined. However, factors which are thought to be associated with dermatomyositis include dysfunction of the immune system Juvenile dermatomyositis presenting with anasarca: a possible indicator of severe disease activity. J Pediatr 2001; 138: 942-945. PubMed CrossRef Google Scholar. 22. Bowyer SL, Clark RA, Ragsdale CG, et al. Juvenile dermatomyositis: histological findings and pathogenic hypothesis for the associated skin changes Juvenile dermatomyositis is an autoimmune disease that causes muscle damage, due to blood vessels that are located under the skin and muscles becoming inflamed. Most commonly, it affects the skin on the knuckles, the edges of the eyelids and the joints of the fingers Recommendations for the diagnosis, treatment, and management of juvenile dermatomyositis (JDM) have been established by a group of European experts in pediatric rheumatology. The guidelines come from the Single Hub and Access Point for Pediatric Rheumatology in Europe (SHARE) initiative and have been recently published in the Annals of the Rheumatic Diseases. Juvenile amyopathic dermatomyositis J Scott Henning DO, Agnieszka Witkiewicz MD, Julie V Schaffer MD, and Seth J Orlow MD PhD Dermatology Online Journal 11 (4): 11 Department of Dermatology, New York University School of Medicine Abstract. A 3-year-old girl presented with a 6-month history of multiple, light-pink, flat-topped papules over the dorsal aspects of the metacarpophalangeal and.

Juvenile Dermatomyositis The Dermatologis

  1. Juvenile dermatomyositis (JDM) is a rare pediatric rheumatic disease. It belongs to the group of idiopathic inflammatory myopathies of childhood. JDM is the most frequent of the idiopathic inflammatory myopathies (it represents 85% of cases) among children. JDM is classified by the Bohan and Peter criteria set in 1975
  2. Juvenile Dermatomyositis in Remission! - Patient L. I was diagnosed with Juvenile Dermatomyositis (JDM) when I was three years old. Prior to getting JDM, I was a healthy, energetic and active boy. It started off as a rash around my face and soon my muscles became very weak
  3. Juvenile dermatomyositis (JDM) is a rare disease that causes muscle inflammation and a skin rash. Symptoms often first appear in children between ages 5 and 10. Symptoms include fever, rash, muscle weakness and pain, and calcium deposits under the skin. The condition also causes a rash around the eyelids, knuckles, or finger joints
  4. Juvenile mysositis is a disease with the hallmark symptoms of muscle weakness and skin rash. The skin rash and weak muscles are caused by inflammation or swelling in the blood vessels under the skin and in the muscles

Cureus Juvenile Dermatomyositis: A Case Report and

  1. A 4-year-old girl with juvenile dermatomyositis presented with weakness, rash, and palpable subcutaneous nodules. A radiograph of the pelvis showed extensive soft-tissue calcinosis. Jianguo Li, M.D
  2. Juvenile dermatomyositis (JDM) is an inflammatory disorder that affects the skin and muscles. All age groups can be affected, but it is most common between the ages of five and 14 years old. Girls are more commonly affected than boys. JDM is part of a group of diseases called idiopathic inflammatory.
  3. Juvenile dermatomyositis has variable clinical presentations both in and outside of pregnancy. A literature review indicated that optimal maternal and fetal outcomes can be anticipated when the pregnancy is undertaken while the disease is in remission. Poorer outcomes are associated with flare-up of the disease in early pregnancy compared with exacerbation in the second or third trimester.
  4. If your child has juvenile dermatomyositis, the experts at Gillette Children's Specialty Healthcare in rheumatology and neuromuscular conditions can offer specialized care to help manage symptoms and improve function.. Kids with JDM require full evaluations, correct diagnoses, and tailored treatments

Prognosis of Juvenile dermatomyositis: The rate of progression is variable but muscle symptoms tend to occur within weeks or months of the skin rash appearing. Steroid treatment is usually very effective.see also Overview of Juvenile dermatomyositis Juvenile dermatomyositis: Research More. Juvenile dermatomyositis: Introductio [Juvenile dermatomyositis (JDM) is the early-onset form of dermatomyositis (DM, see this term), a systemic, autoimmune inflammatory muscle disorder, characterized by proximal muscle weakness, evocative skin lesion, and systemic manifestations., A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash

Juvenile Dermatomyositis Symptoms & Causes Boston

Juvenile dermatomyositis often causes skin rashes, which frequently occur on the face and hands, around the fingernails and over the elbows or knees. Your child's doctor may use a physical exam, blood test, biopsy or MRI to diagnose this condition If your child is battling JM and you'd like to see his or her picture on this page, please send an e-mail containing a digital photo of your child and a short description of your JM experience to While it can occur in people of any age, dermatomyositis typically affects adults in their late 40s to early 60s and is more prevalent among women than men. In children, the onset of juvenile dermatomyositis takes place between 5 and 15. While there's no known cure for dermatomyositis, symptoms can be treated

JDM definisjon: Juvenile Dermatomyositis - Juvenile

Dermatomyositis is one of the idiopathic inflammatory myopathies with characteristic cutaneous manifestations including the heliotrope rash, Gottron's papules, cuticular changes including periungual telangiectasia, a photodistributed erythema or poikiloderma, and a scaly alopecia. Dermatomyositis has been linked to cancer, particularly ovarian cancer Juvenile dermatomyositis is an autoimmune disease marked by muscle weakness and skin rash. The body's immune system attacks blood vessels throughout the body, causing inflammation called vasculitis. Common symptoms reported by people with juvenile dermatomyositis. Common symptoms. How bad it is

What is the abbreviation for Juvenile Dermatomyositis? What does JDM stand for? JDM abbreviation stands for Juvenile Dermatomyositis Adult and juvenile dermatomyositis share the hallmark features of pathognomic skin rash and muscle inflammation, but are heterogeneous disorders with a range of additional disease features and complications. The frequency of important clinical features such as calcinosis, interstitial lung disease and malignancy varies markedly between adult and juvenile disease Background/Purpose: Juvenile dermatomyositis (JDM) is a systemic autoimmune disease with a prominent interferon (IFN) signature. Treatment often requires prolonged high-dose steroids and other immunosuppressive medications. In a compassionate use program, we assessed efficacy and safety of baricitinib (JAK 1/2 inhibitor) in active refractory JDM. Methods: Active (based on ≥3 core set.

Juvenile dermatomyositis - Myositis U

Juvenile Dermatomyositis Lisa G. Rider Juvenile dermatomyositis (JDM) is a systemic autoimmune disease characterized by chronic skeletal muscle and cutaneous inflammation of unknown cause.1,2 Symptoms generally begin before age 18. JDM is relatively responsive to immunosuppressive therapy, and rapid diagnosis, and institution of adequate therapy improves outcomes Human juvenile dermatomyositis (JDM) is the most common childhood inflammatory myopathy (a type of disease affecting muscle and related tissues), causing a characteristic skin rash and progressive muscle weakness beginning around age seven Dermatomiositis Juvenil ¿Qué es la dermatomiositis juvenil? La dermatomiositis juvenil es uno de los trastornos de un grupo de trastornos denominado complejo dermatomiositis-polimiositis Dermatomyositis is a rare inflammatory condition that causes muscle weakness and a red rash. Here are the causes, symptoms, treatment, and recommended die Uttaleguide: Lær hvordan juvenile dermatomyositis uttales på Engelsk med innfødt uttale. juvenile dermatomyositis Engelsk oversettelse

Juvenile dermatomyositis - Wikipedi

The childhood form (juvenile dermatomyositis) is sensitive to steroids and many children will respond, whereas the adults are much more variable. Immunosuppressants. A second line of treatment is immunosuppressive medication. Like steroids, these drugs suppress the body's immune system and limit the inflammation Juvenile Dermatomyositis (JDM), Southampton, United Kingdom. 1,952 likes · 3 talking about this. A page for the JDM. Under the umbrella of Myositis UK. Administrated by JDM mums Kathryn and JDM now..

Juvenile Dermatomyositis Outlook / Prognosis Cleveland

A 16 year old girl is referred to the dermatology department because of complaints of progressive sunken skin lesions on arms and legs. Besides that, she als

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